Engineering-Style QSP Modeling with Heta

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February 25, 2026

InSysBio announces the upcoming workshop on Heta at Quantitative Systems Pharmacology Conference (QSPC 2026). The worksop will be held at Golden Tulip & Tulip Inn Leiden Centre, Leiden, the Netherlands on April 7, 2026, 1 PM – 5 PM.

This workshop introduces an engineering-oriented approach to quantitative systems pharmacology (QSP) modeling using the Heta language and its associated tools. The session focuses on how structured, modular, and process-based model descriptions can improve transparency, reuse, and reproducibility compared to traditional monolithic ODE-based workflows. Participants will be introduced to the core concepts of the Heta language, including process-based model formulation, modularization, and alternative model representations, with an emphasis on how these ideas support scalable QSP workflows rather than on detailed syntax or implementation.

The workshop demonstrates how Heta models are used in practice: from model specification to translation into standard formats and execution with different simulation tools. The session includes guided demonstrations of model conversion using the Heta compiler, basic simulation workflows with HetaSimulator, and an overview of a typical Heta project structure. Short, optional hands-on segments are included for participants who wish to follow along, while others may simply observe the demonstrations. The workshop is intended as an accessible entry point for researchers interested in engineering-style QSP workflows and evaluating whether such an approach fits their existing modeling practice.

What You Will Learn

  • The core principles of the Heta language for QSP modeling, including process-based model formulation and modular model structure
  • How Heta models can be translated into multiple standard formats using the Heta compiler and integrated with existing modeling environments
  • The basic workflow for running simulations and structured experiments using HetaSimulator
  • The typical organization of a Heta project, including model, module, and scenario components
  • Practical considerations for applying an engineering-style workflow to real-world QSP modeling tasks

Who Should Attend

  • Students and early-career researchers who want an accessible introduction to structured, code-based QSP model development
  • Practicing QSP modelers interested in improving flexibility, modularity, reproducibility, and scalability of their modeling workflows
  • Scientists and developers who work with QSP models across multiple tools/formats and want a more systematic way to organize, reuse, and translate models

The workshop is free of charge.

Register here

About InSysBio

InSysBio is a group of Quantitative Systems Pharmacology (QSP) companies located in Limassol, Cyprus (INSYSBIO CY Ltd) and Edinburgh, UK (INSYSBIO UK LIMITED). InSysBio was founded in 2004 and has an extensive track record of helping pharmaceutical companies to make right decisions on the critical stages of drug research and development by application of QSP modeling. InSysBio's cutting-edge QSP approach has already become a part of the drug development process implemented by our strategic partners: there are more than 100 completed projects in collaboration with leaders of pharmaceutical industry and innovative biotech companies. For more information about InSysBio, its solutions and services, visit www.insysbio.com

 

October 2018
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1. 01 Oct 2018 12:23 InSysBio Announces Continuation of Collaboration with MedImmune for Quantitative Systems Pharmacology Modeling in Systemic Lupus Erythematosus InSysBio, a pioneer in Quantitative Systems Pharmacology (QSP), modeling and simulation for drug development, announced today an extension of a collaboration with MedImmune, the global biologics research and development arm of AstraZeneca, for QSP modeling in systemic lupus erythematosus (SLE). The goal is to support the clinical development of anifrolumab, an investigational monoclonal antibody against the type I interferon receptor, by modeling the contributions of key cell types involved in the pathophysiology of lupus that are associated with the type I interferon dysregulation commonly seen with the disease.
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1. 02 Oct 2018 14:05 InSysBio to present at ACoP9 InSysBio announces their participation at Ninth American Conference on Pharmacometrics (ACoP9), to be held October 7th to 10th, 2018, at the Loews Coronado Bay Resort near San Diego, CA. The theme of ACoP9 is “Modeling without Bounds”. InSysBio welcomes visitors at the booth #23.
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1. 09 Oct 2018 15:29 InSysBio starts training course “Modeling for systems biology and biomedicine” InSysBio expert modelers Dr. Galina Lebedeva, Dr. Tatiana Karelina, Dr. Evgeny Metelkin and Dr. Oleg Demin will give the course “Modeling for systems biology and biomedicine” at the Faculty of bioengineering and bioinformatics, Lomonosov Moscow State University.
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1. 19 Oct 2018 15:49 InSysBio to present at BiotechClub 2018 InSysBio announces their participation at BiotechClub 2018 conference to be held on October 26th at Hyatt Regency Moscow Petrovsky Park. The theme of BiotechClub 2018 is “From Systems Biology to Systems Medicine”.
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1. 24 Oct 2018 13:49 InSysBio to present at ICSB 2018 InSysBio announces their participation at 19th International Conference on Systems Biology (ICSB 2018) to be held October 28th to November 1st, 2018 in Lyon, France.
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