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Press-Release
October 29, 2025
InSysBio to announce its collaboration with BeOne Medicines

The project aims at mechanistic PK/RO modeling to predict optimal dose and regimen of BGB-B2033, GPC3 x 4-1BB bispecific antibody

InSysBio, one of the world's pioneers of Quantitative Systems Pharmacology (QSP) modeling, announces its collaboration with BeOne Medicines, a global oncology company.
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NEWS
Software
Press-Release
October 16, 2025
InSysBio to introduce a new data annotation service available in CYTOCON DB and fIVE DB
InSysBio launches a new data annotation service designed to support researchers and analysts who require specific, literature-based biological data to be added to InSysBio’s CYTOCON or fIVE databases for use in QSP modeling, analysis, or decision-making. The new service allows clients to submit targeted data requests related to diseases, tissues, cell types, and cytokines
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NEWS
Publication
August 19, 2025
InSysBio to publish the new article "Revolutionizing drug discovery: Integrating artificial intelligence with quantitative systems pharmacology"
The new article “Revolutionizing drug discovery: Integrating artificial intelligence with quantitative systems pharmacology” by Igor Goryanin, Irina Goryanin, Oleg Demin was published in Drug Discovery Today on August 6, 2025
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NEWS
Press-Release
Software
August 5, 2025
InSysBio to launch Immune Response Template Open for QSP modeling
InSysBio announces Immune Response Template (IRT) which was previously available under a license model now is completely free to use. IRT represents a QSP platform of immune system, simultaneously, being a tool for development of models related to immune system.
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NEWS
Press-Release
June 25, 2025
InSysBio to announce extension of collaboration with discoveric bio alpha

The project aims at translational mechanistic modeling of antibodies to predict human pharmacokinetics and target occupancy in cerebrospinal fluid

InSysBio, one of the world’s pioneers of Quantitative Systems Pharmacology (QSP) modeling, announces the extension of collaboration with discoveric bio alpha, a biotechnology company taking next generation antibody technologies into Alzheimer’s Disease.
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NEWS
Publication
June 18, 2025
InSysBio to publish the new article in CPT: Pharmacometrics & Systems Pharmacology
The new article “Quantitative Systems Pharmacology Model That Describes Neurofilament Light Dynamics During Alzheimer's Disease Progression” by Polina Maliukova, Tatiana Karelina was published in CPT: Pharmacometrics & Systems Pharmacology Journal on June 17, 2025
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November 2018
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1. 06 Nov 2018 17:27 Investigation of amyloid pathology mechanisms and prediction of clinical trial results using QSP model InSysBio presents the video of Tatiana Karelina’s talk in framework of session “From translational PKPD models to quantitative system pharmacology in neurodegeneration drug development” at the 9th American Conference on Pharmacometrics (ACoP9):
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1. 26 Nov 2018 14:03 InSysBio updates Immune Response Template online InSysBio, a pioneer in Quantitative Systems Pharmacology (QSP) modeling and simulation for drug development, today announced a release of updated version of Immune Response Template (IRT) online. The main update in new 2.1.0 version is myeloid-derived suppressor cells (MDSCs). Published human in vitro and in vivo data were analyzed to reconstruct monocytic MDSCs (Mo-MDSCs) and granulocytic MDSCs (Gr-MDSCs) life cycles, derive equations and identify parameters.
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