InSysBio, one of the world’s pioneers of Quantitative Systems Pharmacology (QSP) modeling, announces its collaboration with discoveric bio alpha, a biotechnology company taking next generation antibody technologies into Alzheimer’s Disease.
Mechanistic modeling will be leveraged to simulate pharmacokinetics (PK) and target occupancy (TO) in cerebrospinal fluid (CSF) of NIDB-3101 being developed by discoveric bio alpha.
Jean-Philippe Courade, CSO of discoveric bio alpha, highlights, “We are excited to implement InSysBio’s solutions and wide-ranging modeling experience to enhance the design of preclinical study of NIDB-3101. We hope mechanistic modeling will facilitate accurate dose selection thus accelerating and optimizing further development of our antibody”.
Oleg Demin Jr, Scientific Director, InSysBio, comments on the new project, “Our cutting-edge mechanistic modeling approach along with our expertise in modeling of therapeutic antibodies enable us to efficiently develop the PK/TO model based on the published data for other mAbs. We look forward to apply our knowledge and software to support optimization of the experiment design”.
About InSysBio
InSysBio is a group of Quantitative Systems Pharmacology (QSP) companies located in Limassol, Cyprus (INSYSBIO CY Ltd) and Edinburgh, UK (INSYSBIO UK LIMITED). InSysBio was founded in 2004 and has an extensive track record of helping pharmaceutical companies to make right decisions on the critical stages of drug research and development by application of QSP modeling. InSysBio’s cutting-edge QSP approach has already become a part of the drug development process implemented by our strategic partners: there are more than 100 completed projects in collaboration with leaders of pharmaceutical industry and innovative biotech companies. For more information about InSysBio, its solutions and services, visit www.insysbio.com
About discoveric bio alpha
discoveric bio alpha is a privately owned company part of a group of three separate companies dedicated to the development of novel therapeutics for the treatment of Alzheimer’s Disease, Neuroinflammation and Antimicrobial Resistant infections. It is located in Pfäffikon, Switzerland. For more information, visit https://www.discovericbio.com/
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19 Feb 2020 12:54
InSysBio to participate in ASCPT 2020
InSysBio announced its participation in 121st Annual meeting of American Society for Clinical Pharmacology and Therapeutics (ASCPT 2020) which is to be held on March 18-21, 2020 at Marriott Marquis Houston, TX. InSysBio welcomes visitors at the booth # 102. Oleg Demin, CEO of InSysBio, Tatiana Karelina, lead modeler in Alzheimer's Disease and Veronika Musatova, Head of IRT development team, will present the new version of IRT (Immune Response Template) and Cytocon DB (Cell and cYTOkine CONcentrations).
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21 Feb 2020 17:02
InSysBio presents an enhanced version of its Immune Response Template Database
IRT Version 3.0.0 acquires a wide variety of updates and new options
(Moscow – 21.02.2020) InSysBio, one of the world’s pioneers of Quantitative Systems Pharmacology (QSP) platform development and provision, moves forward to the future.
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