InSysBio, one of the world’s pioneers of Quantitative Systems Pharmacology (QSP) modeling, announces its collaboration with discoveric bio alpha, a biotechnology company taking next generation antibody technologies into Alzheimer’s Disease.
Mechanistic modeling will be leveraged to simulate pharmacokinetics (PK) and target occupancy (TO) in cerebrospinal fluid (CSF) of NIDB-3101 being developed by discoveric bio alpha.
Jean-Philippe Courade, CSO of discoveric bio alpha, highlights, “We are excited to implement InSysBio’s solutions and wide-ranging modeling experience to enhance the design of preclinical study of NIDB-3101. We hope mechanistic modeling will facilitate accurate dose selection thus accelerating and optimizing further development of our antibody”.
Oleg Demin Jr, Scientific Director, InSysBio, comments on the new project, “Our cutting-edge mechanistic modeling approach along with our expertise in modeling of therapeutic antibodies enable us to efficiently develop the PK/TO model based on the published data for other mAbs. We look forward to apply our knowledge and software to support optimization of the experiment design”.
About InSysBio
InSysBio is a group of Quantitative Systems Pharmacology (QSP) companies located in Limassol, Cyprus (INSYSBIO CY Ltd) and Edinburgh, UK (INSYSBIO UK LIMITED). InSysBio was founded in 2004 and has an extensive track record of helping pharmaceutical companies to make right decisions on the critical stages of drug research and development by application of QSP modeling. InSysBio’s cutting-edge QSP approach has already become a part of the drug development process implemented by our strategic partners: there are more than 100 completed projects in collaboration with leaders of pharmaceutical industry and innovative biotech companies. For more information about InSysBio, its solutions and services, visit www.insysbio.com
About discoveric bio alpha
discoveric bio alpha is a privately owned company part of a group of three separate companies dedicated to the development of novel therapeutics for the treatment of Alzheimer’s Disease, Neuroinflammation and Antimicrobial Resistant infections. It is located in Pfäffikon, Switzerland. For more information, visit https://www.discovericbio.com/
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02 Aug 2021 16:17
InSysBio to take part in PharmSci360 2021
InSysBio announces its participation in AAPS 2021 PHARMSCI 360 which is to be held in Pennsylvania Convention Center, Philadelphia, PA, and Online 17-20 October, 2021. InSysBio team is going to present the update at the Virtual Booth (VB1) and 2 posters in frames of the Conference
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06 Aug 2021 15:38
InSysBio to participate in Biomarkers for Alzheimer’s Disease Summit
InSysBio will take part in Annual Biomarkers for Alzheimer’s Disease Summit, Digital Event which is going to be held August 24-26, 2021. InSysBio will present its Neurodegeneration modeling issues and Alzheimer’s Disease Platform update at its Virtual Booth! Moreover, Tatiana Karelina, Head of Neurodegenerative Diseases Modeling Team, will give a talk
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11 Aug 2021 15:50
InSysBio to launch its OpenSource HetaSimulator project
The new platform is a part of Heta-based QSP modeling infrastructure
[Moscow – 11.08.2021] InSysBio, one of the world’s pioneers of Quantitative Systems Pharmacology (QSP) modeling, now presents HetaSimulator. It is a part of Heta project that embraces three components. HetaSimulator is an OpenSource simulation and parameters estimation platform for the Heta modeling language.
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18 Aug 2021 10:49
InSysBio to take part in PAGE 2021
InSysBio announces its participation in PAGE 2021 Online meeting which is to be held on the 2nd, 3rd, 6th, and 7th of September 2021. InSysBio team is going to present its latest development at the Virtual Exhibition e-booth and six posters
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