2021
ACoP12 Virtual Conference
HetaSimulator is an Open Source Simulation and Parameter Estimation Software for QSP Modeling
Authors: Ivan Borisov, Evgeny Metelkin
Semi-mechanistic PK/PD modeling of anti-CD47 therapeutic agent
Authors: Elena Vasileva, Oleg Demin Jr
A Quantitative Systems Pharmacology Model of adverse effects of PI3K? inhibitors on intestine inflammation
Authors: Sergey Smirnov 1, Oleg Demin 1, Erqian Yu 2, Xiaomin Song 2, Sri Sahasranaman 2, Yan Ren 2
Affiliation: 1 InSysBio, Moscow, Russia; 2 BeiGene, Beijing, China
Application of CYTOCON DB to compare cell/cytokine profile of patients with melanoma, NSCLC, and healthy subjects
Authors: Vladislav Leonov, Ekaterina Mogilevskaya, Elita Gerasimuk, Nikolay Pervushin, Nail Gizzatkulov, Oleg Demin
Investigation of inflammation during Alzheimer's disease by quantitative systems pharmacology model
Authors: Andrey Masliukov, Tatiana Karelina
PBPK modeling of T cell distribution in cancer patients
Authors: Dmitry Shchelokov 1, Oleg Demin Jr 1, Sara Brett 2 , Stefan Zajic 3, Lourdes Cucurull-Sanchez 2
Affiliation: 1 InSysBio, Moscow, Russia; 2 GlaxoSmithKline, Stevenage, Hertfordshire, UK; 3 GlaxoSmithKline, Upper Providence, PA, USA
Development of QSP model of COVID-19 based on Immune Response Template
Authors: Veronika Musatova, Oleg Demin, Maria Kupriyanova, Anna Viktorenko
PBPK/RO modeling of anti-PDL1 antibodies
Authors: Antonina Nikitich, Oleg Demin Jr
Quantitative systems pharmacology model for neurofilament L dynamics in Alzheimer's disease pathology
Authors: Polina Pchelintseva, Tatiana Karelina
The QSP model of amyloid beta and tau oligomers influence on synaptic plasticity
Authors: Stepan Lerner, Tatiana Karelina
Comparison Of Different Approaches To Generate Virtual Patient Populations Of Different Sizes For QSP Model Of Erythropoiesis
Authors: Galina Kolesova, Oleg Demin, Alexander Stepanov
Heta language: Modularity and Reusability in QSP modeling platforms
Authors: Evgeny Metelkin
AAPS 2021 PHARMSCI 360, Online
Application of Immune Response Template to Develop QSP Model of COVID-19
Authors: Veronika Musatova, Oleg Demin, Maria Kupriyanova, Anna Viktorenko
ESMO Virtual Congress 2021
Selection of the optimal dose for ALX148, a CD47 blocker, using pharmacokinetic/pharmacodynamic modeling
Authors: Elena Vasileva 1,2, Oleg Demin Jr ?2
Affiliation: 1 Lomonosov Moscow State University, Moscow, Russia; 2 InSysBio, Moscow, Russia
PAGE 2021, Online meeting
Quantitative systems pharmacology model of axonal degeneration markers in Alzheimer’s disease
Authors: Tatiana Karelina, Polina Pchelintseva
Virtual Patient Populations: Comparison of Approaches in Application to QSP Model Of Erythropoiesis
Authors: Galina Kolesova, Oleg Demin, Alexander Stepanov
HetaProject – a Single Open Source Platform for Modeling, Simulation and Parameters Estimation in QSP
Authors: Ivan Borisov, Evgeny Metelkin
CYTOCON DB as storage of unified data on in vivo human concentrations of cells and molecules in health and disease
Authors: Ekaterina Mogilevskaya, Vlad Leonov, Elita Gerasimuk, Nikolay Pervushin, Nail Gizzatkulov, Oleg Demin
Annual Biomarkers for Alzheimer’s Disease Summit, Digital Event
Mechanistic modeling approach to prediction and analysis of clinical trial results in neurodegeneration area
Authors: Tatiana Karelina
AAIC 2021 Online
Quantitative systems pharmacology model of amyloid and tau to explore efficacy of therapy targeting modified forms of amyloid
Authors: Tatiana Karelina
Quantitative systems pharmacology model of the effect of tau hyperphosphorylation on synaptic plasticity
Authors: Stepan Lerner, Tatiana Karelina
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